I have talked about my continual battle with depression on this blog before, and today, I saw something that I felt compelled to discuss. First of all, I should mention, in case it isn’t “known”, that I take a SSRI for my depression. I have for a long time, and often times, I wonder if it even works, because I still find that I go through bouts of moderate to severe depression. Well, after reading this, I can’t help but wonder if the medication is actually “treating” the depression.
In the article, they discuss a study that was done to compare the “clinical effectiveness” of several SSRIs (mine is listed), in order to see if the benefit of the drug was more than a simple placebo. What’s interesting, is that they found that across the board for those drugs that they looked it, it wasn’t (except in cases of extreme depression). This makes me wonder about the drug that I take every morning to “prevent” my depression; especially since, as I mentioned, it hasn’t actually gone away at any time during the course of my “treatment”.
I am not saying that I don’t believe the drugs have any benefit. Even the placebo effect is proven to have a benefit, and that may account for some of these findings. However, I do think that it is easy to wonder, that if you take drugs to help with a problem, and the problem doesn’t seem to want to go away, then perhaps those drugs aren’t working for you. The article also mentioned that trying therapy first would probably be a new recommendation; but I did that, and still ended up taking medication, a medication that I am now even more curious about.
I know that the medication must have some benefits. I don’t have anxiety as intense as I did before I took (at least I don’t think that I do). I also know (through the magic of therapy), that my depression is more likely than not, tied to my anxiety. So, if the medication is working on the anxiety, but it doesn’t have an effect on the depression, what does that mean? Should I be taking a different class of medication to deal with the depression as well? Or, am I “better” than I was before, and I just don’t know it? Maybe the drugs are working, and I just don’t know the difference because I have been taking them so long? I find myself riddled with questions right now.
This is something that I think might be worth exploring further. I may make a doctor’s appointment to find out more about what may or may not be a better option for me.
One issues I do have, is that the article goes so far as to say that the medications “don’t work”, citing it is below clinical significance. That is to say, that just because it wasn’t statistically significant, they have proven that it doesn’t work; which really doesn’t make sense, if it did work on the minority of those “not-statistically-significant-so-forget-them” patients. This is where the cynic about clinical research in me steps in, because I always question its reliance on numbers, and a lack of perspective on the individual that may benefit… In the case of a drug that MAY benefit some that has very few side effects (for adults), why would they declare that it simply doesn’t work, just because it doesn’t work more often than not? Additionally, if it doesn’t work most of the time, why have they waited until now to tell people that are taking it?
What’s your take on this? If you take one of these medications, is this going to effect your future treatment? Does it concern you that your medication may not be doing what you need it to? What do you think?